Myc

They transplanted Myc-driven lymphoma cells into wild-type mice and then turned on p53 expression in the lymphoma cells.

他们将原癌基因诱导的淋巴瘤移植到野生型小鼠，然后在淋巴瘤细胞启动p53表达。

That is because one of Dr Yamanaka´s transcription factors, c-Myc, sometimes has the unfortunate side-effect of causing cancer.

Yamanaka博士发现的转录因子有时会导致癌症的产生。

The first involved safety, since the technique relied on potentially harmful genetic manipulation, and worse yet, the insertion of two known cancer-causing genes (c-Myc and Oct4).

其一是安全性的问题，因为该技术是基于具有潜在伤害性的基因操作，并且引入了2个致癌基因(c - My c and Oct4)。