穿心莲内酯

The present invention is one kind of soft andrographolide capsule preparation and its preparation process.

本发明为一种穿心莲内酯软胶囊的制剂及其制备方法。

AIM: To study the synthesis and antitumor activity of the andrographolide derivatives.

目的：设计和合成出新的穿心莲内酯衍生物并研究其抗肿瘤活性。

Orthogonal experiments were used to find the optimal extraction process of andrographolide by microwave and ultrasonic assisted extraction.

用正交法对微波和超声波辅助提取穿心莲内酯的工艺条件进行优化。

Result:The tests results proved to us that the peak of Dehydroandrographolide would drop as the Dehydroan-drographolide CRS was evaporated in a water bath.

结果：发现水浴蒸干会使脱水穿心莲内酯的色谱峰峰面积积分值大大降低。

METHODS Gradient elution method was used to determine the content of andrographolide and dehydroandrographolide in Qinghuo Zhimai tablets.

方法：用梯度洗脱法测定清火栀麦片中穿心莲内酯和脱水穿心莲内酯的含量。